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so let's talk about that first the 4.64 Jump to 28.4
    ORDINAL first
of starting the discussions of a fourth 5.679 Jump to 33.04
    ORDINAL fourth
first let's look at the short term i 4.32 Jump to 52.64
    ORDINAL first
fall of 2022 you know we're very blessed 5.601 Jump to 132.319
    DATE 2022
that in 21 you know we just announced we 6.56 Jump to 135.36
    CARDINAL 21
shipped 807 million dollars 25 of those 6.319 Jump to 137.92
    MONEY 807 million dollars
    CARDINAL 25
and uh that translates into around 17.5 5.6 Jump to 146.16
billion of sales for 21. when i think we 5.12 Jump to 148.8
    DATE 21
our expectations for sales for 22. 5.92 Jump to 153.92
    CARDINAL 22
on on november 4th quarterly call we had 5.52 Jump to 157.12
    DATE november 4th
    DATE quarterly
with down payments for 17 billion for 6.08 Jump to 162.64
    CARDINAL 17 billion
2022 and we had options for up to three 4.16 Jump to 165.84
    CARDINAL up to three
billion 3.28 Jump to 168.72
apas for 18.5 billion 5.52 Jump to 175.04
    MONEY 18.5 billion
of 2022 4.48 Jump to 184.0
    DATE 2022
and the options have now gone up to 3.5 5.199 Jump to 185.68
    CARDINAL up to
    CARDINAL 3.5
billion a dollar but what it's important 3.92 Jump to 188.48
discussions ongoing for the fall of 2022 5.919 Jump to 192.4
    DATE the fall of 2022
tilted toward the first half of the year 4.56 Jump to 198.319
    DATE the first half of the year
governments get ready for 22 and already 4.561 Jump to 202.879
    DATE 22
orders for 23 like the uk and taiwan who 4.96 Jump to 207.44
    CARDINAL 23
which is that 2022 was really where 4.08 Jump to 217.36
    DATE 2022
low-income countries there's two pieces 3.2 Jump to 248.56
    CARDINAL two
first half to maybe up to september 5.681 Jump to 257.759
of 2021 there was a supply issue you 4.4 Jump to 260.88
    DATE 2021
given day of the week we had between 50 5.04 Jump to 281.52
    DATE given day of the week
    CARDINAL between 50
and 100 million doses sitting in the 3.36 Jump to 284.32
    CARDINAL 100 million
their q2 reservation which was for 60 5.28 Jump to 300.0
    CARDINAL 60
million doses they do not need it 5.759 Jump to 302.72
especially for 22 for moderna beyond the 6.0 Jump to 376.8
    CARDINAL 22
while the kobe 19 vaccine is very 3.28 Jump to 396.639
    CARDINAL 19
know 17.5 billion last year as i said 5.68 Jump to 401.44
    MONEY 17.5 billion
    DATE last year
already 18.5 signed for this year plus 4.961 Jump to 404.319
    CARDINAL 18.5
    DATE this year
modena has built a platform for 10 years 5.521 Jump to 414.319
    DATE 10 years
finished 2021 with 17 billion dollar of 5.6 Jump to 419.84
    DATE 2021
    MONEY 17 billion dollar
know we invested in 2019 free pandemic 5.761 Jump to 431.039
    DATE 2019
500 million dollar in r d well guess 6.08 Jump to 434.08
    MONEY 500 million dollar
what this year our plan is to invest 2.5 6.239 Jump to 436.8
    DATE this year
    CARDINAL 2.5
to 3 billion that's five to six x more 6.159 Jump to 440.16
    CARDINAL 3 billion
    CARDINAL five to six
investment and we have now 40 programs 5.28 Jump to 443.039
    CARDINAL 40
know we invested less than 100 million 3.759 Jump to 452.56
    MONEY less than 100 million
in 2019 3.04 Jump to 454.8
    DATE 2019
around 800 million 4.24 Jump to 457.84
    CARDINAL around 800 million
getting one product to market 2.72 Jump to 476.72
    CARDINAL one
440 4.241 Jump to 481.599
    CARDINAL 440
one single dose a year you get your 4.479 Jump to 488.4
    CARDINAL one
there are around 10 4.641 Jump to 498.879
    CARDINAL around 10
those 10 viruses so people don't get 4.56 Jump to 513.68
    CARDINAL 10
in 2022 people should not be dying of 4.08 Jump to 520.56
    DATE 2022